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symmetric rash on the palms and soles.Illustration of secondary syphilis rash on the palms - small symmetric reddish-brown copper-coloured spots. https://hisential.com/assets/secondary-syphilis-palms-soles-rash-BlZC5OqM.jpgSecondary syphilis - copper-coloured spots on the palms and soles.Illustration of secondary syphilis rash showing copper-coloured macules across both palms. https://hisential.com/assets/hiv-seroconversion-rash-B2dUcdAj.jpgAcute HIV - diffuse trunk rash with flu-like illness 2 - 4 weeks after exposure.Illustration of acute HIV seroconversion rash - diffuse pink maculopapular spots across the chest and upper trunk. https://hisential.com/assets/herpes-rash-vesicles-DbvBx26H.jpgHerpes - grouped vesicles on a red base, typically painful or tingling.Illustration of a herpes simplex outbreak - clustered clear vesicles on a pink erythematous base. https://hisential.com/assets/hepatitis-b-rash-DvleWJKa.jpgAcute hepatitis B - urticarial rash can accompany fatigue and jaundice.Illustration of an acute hepatitis B urticarial rash on a forearm - raised pale-pink wheals. https://hisential.com/symptoms/lumps-and-bumps2026-06-25monthly0.80 https://hisential.com/assets/hpv-genital-warts-CK37fmKa.jpgHPV genital warts - soft cauliflower-like growths, treated in clinic with cryotherapy or topical therapy.Illustration of HPV genital warts - soft cauliflower-like flesh-coloured papules clustered on skin. https://hisential.com/assets/primary-syphilis-chancre-fvigo7hs.jpgPrimary syphilis - a single painless ulcer that heals on its own without treatment.Illustration of a primary syphilis chancre - single round painless ulcer with a clean indented base and raised border. https://hisential.com/assets/hpv-genital-warts-CK37fmKa.jpgHPV warts - usually painless, treated in-clinic; partners benefit from HPV vaccination.Illustration of HPV genital warts - clustered soft cauliflower-like flesh-coloured papules. https://hisential.com/assets/molluscum-contagiosum-lKrHvcS4.jpgMolluscum contagiosum - pearly papules with a central dimple; cleared in clinic.Illustration of molluscum contagiosum - pearly dome-shaped papules with central umbilication on skin. https://hisential.com/assets/herpes-genital-vesicles-BxrLPAiL.jpgHerpes - painful grouped blisters on a red base, controlled with antivirals.Illustration of a genital herpes outbreak - clustered clear vesicles on a red base, some lightly crusted.